KTH Royal Institute of Technology, School of Engineering Sciences

Project description

Third-cycle subject: Physics - specialization Biological and Biomedical Physics

Membrane proteins, such as ion channels, enable cells to communicate with the outside world and are important pharmacological targets. The study of their function can be hampered by limitations in the experimental setups, making computer simulations a complementary tool of choice to investigate the details of their mechanics.

However, ion channel gating and allosteric regulation involves conformational changes occurring over time scales that are typically longer than the ones that can be directly observed using MD simulations. The project thus involves developing protocols that allow to sample these conformational changes using enhanced sampling techniques, by taking advantage of what is already known about the process (via interpretation of experimental results and/or long time-scale simulations). In a second step, the simulation output will be analyzed and interpreted.

The work in the group is highly international and cross-disciplinary. You will be a member of a research team with high-paced work, and the project includes collaborations with our international partner groups in the US.

What we offer

Eligibility

To be admitted to postgraduate education (Chapter 7, 39 § Swedish Higher Education Ordinance), the applicant must have basic eligibility in accordance with either of the following:

  • passed a degree at advanced level,
  • completed course requirements of at least 240 higher education credits, of which at least 60 higher education credits at advanced level, or
  • in any other way acquired within or outside the country acquired essentially equivalent knowledge.
  • experience with simulations of membrane proteins, enhanced sampling techniques and/or interfacing with experiments on membrane proteins will be an advantage.
  • The successful candidate is expected to have a Master's degree in physics, chemistry, biochemistry or biotechnology.  

Selection

In order to succeed as an doctoral student at KTH you need to be goal oriented and persevering in your work. In the selection of the applicants, the following will be assessed:

  • ability to independently pursue his or hers work,
  • ability to collaborate with others,
  • have a professional approach,
  • analyse and work with complex issues,
  • experience with simulations of membrane proteins, enhanced sampling techniques and/or interfacing with experiments on membrane proteins will be an advantage and
  • note that a good command of English is essential, both as the local working language and because of our international collaborations

Target degree: Doctoral degree

Information regarding admission and employment

Only those who are or have been admitted to third-cycle studies may be employed as a doctoral student. The term of the initial contract may not exceed one year and may thereafter be extended. Doctoral students may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.

Union representatives

You will find contact information for union representatives on KTH's website.

Doctoral section (Students’ union on KTH Royal Institute of Technology)

You will find contact information for doctoral section on the section's website.

Application

Apply for the position and admission through KTH's recruitment system. It is the applicant’s responsibility to ensure that the application is complete in accordance with the instructions in the advertisement.

Applications must be received at the last closing date at midnight, CET/CEST (Central European Time/entral European Summer Time).

Applications must include the following elements:

  • CV including your relevant professional experience and knowledge.
  • Application letter with a brief description of why you want to pursue research studies, about what your academic interests are and how they relate to your previous studies and future goals. (Maximum 2 pages long)
  • Copy of the degree certificate(s) and transcripts of records from your previously attended university-level institutions. Translations into English or Swedish if the original documents are not issued in one of these languages.
  • Representative publications or technical reports. For longer documents, please provide a summary (abstract) and a web link to the full text.

Other information

Gender equality, diversity and zero tolerance against discrimination and harassment are important aspects of KTH's work with quality as well as core values in our organization.

For information about Processing of personal data in the recruitment process please read here.

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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.

Type of employment Temporary position
Contract type Full time
First day of employment According to agreement
Salary Monthly salary according to KTH's doctoral student salary agreement
Number of positions 1
Full-time equivalent 100%
City Stockholm
County Stockholms län
Country Sweden
Reference number S-2018-1712
Contact
  • Lucie Delemotte, e-mail: lucied@kth.se
Published 06.Dec.2018
Last application date 31.Dec.2018 11:59 PM CET

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