Researcher Therapeutic Protein Engineering at the DDD platform

Job description

The Drug Discovery & Development platform at the Science for Life Laboratory (SciLifeLab DDD) is a national infrastructure for academic drug development with the task of translating academic discoveries into drug candidates for further commercial development. The business, which has existed for almost ten years, has, among other things, contributed to >10 new companies and four clinical drug candidates. The platform includes around 40 employees at six Swedish universities who all support collaborative projects with external academic project owners.

The DDD unit "Therapeutic Protein Engineering" (TPE) is attached to KTH and located at SciLifeLab DDD, Solna. The unit's main responsibility is to deliver well-characterized antibodies, antigens, and target proteins to the projects, as well as be technically responsible for the selection-based projects.

Your tasks will be to develop expression and purification protocols for challenging target proteins in our drug discovery projects, as well as to analyze and characterize protein properties such as functionality and conformation using various biochemical and biophysical techniques. Your role will be both lab-based and coordinative.

What we offer

• A position at a leading technical university that generates knowledge and skills for a sustainable future.
• Engaged and ambitious colleagues along with a creative, international and dynamic working environment
• Work in Stockholm , in close proximity to nature
• Help to relocate and be settled in Sweden and at KTH

Read more about what it is like to work at KTH

Qualifications

Requirements

• A doctoral degree or an equivalent foreign degree in biotechnology, biochemistry or molecular biology
• Thorough experience in cloning, overexpression and purification of proteins in bacteria, insect cells and/or mammalian cells
• Protein purification using ÄKTA or comparable systems
• Thorough knowledge of standard protein analysis methods
• Experience with biophysical protein analysis methods, e.g. ITC, DLS and DSF 
• High level of independence and good collaborative abilities

Preferred qualifications

•  Experience from biotech/pharmaceutical industry or relevant academic research environment
• Experience with structural biology, especially cryo-EM
• Experience with SPR
• Experience with protein engineering
• Excellent writing and communication skills
• Project management and coordination
• Knowledge of diversity and equal opportunity issues, with specific focus on gender equality 

Great emphasis will be placed on personal skills.

Trade union representatives

You will find contact information to trade union representatives at KTH's webbpage.

To apply for the position

Log into KTH's recruitment system in order to apply for this position. You are the main responsible to ensure that your application is complete according to the ad. Your complete application must be received at KTH no later than the last day of application.

The application must contain:

1. CV including relevant professional experience and knowledge.
2. Copy of diplomas and grades from your previous university studies. Translations into English or Swedish if the original documents are not issued in either of these languages.
3. Personal letter (1 page)

Your complete application must be received by KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time). 

About the employment

The employment is valid until further notice (permanent post) according to agreement.
The employment begins with a six-month probationary period.

Other information

Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.

For information about processing of personal data in the recruitment process please read here.

The position may include security-sensitive activities. To become authorized, you therefore need to pass a possible security check.

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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence