Researcher in cell line engineering for biologics production

Job description

Gene therapies based on viral vectors are on the rise, and in recent years several new drugs based on adeno-associated viruses (AAV) have reached patient and market approvals. A challenge to realizing the availability of these life-changing advanced therapies is to simplify and improve their manufacturing process.

We are therefore currently looking for a researcher who will work with a team to lead, research and lead the development of refined mammalian cell lines for the production of biological drugs, such as AAV, protein and antibodies. The person we are looking for will have tasks that revolve around OMICS, genome changes with CRISPR/Cas9, protein and virus production in mammalian cells as well as their purification, quantification and analysis. The person will work with various methods such as NGS sequencing, molecular cloning, ELISA, protein expression and affinity determinations.

What we offer

• A position at a leading technical university that generates knowledge and skills for a sustainable future.
• Engaged and ambitious colleagues along with a creative, international and dynamic working environment
• Work in Stockholm , in close proximity to nature
• Help to relocate and be settled in Sweden and at KTH

Read more about what it is like to work at KTH.

Qualifications

Requirements

• A doctoral degree or an equivalent foreign degree
• Knowledge and experience in bioinformatics and programming
• Good knowledge of biological drugs and viral vectors for gene therapy applications.
• Experience working with or producing viral vectors
• Experience in molecular biology methods such as RNAseq analysis, cloning, immunoprecipitation, microscopy, ELISA and western blotting 
• We are looking for you with scientific skill, good problem-solving skills and good scientific integrity
• You work in a structured way and are responsible
• You have good collaboration skills but can also work independently 
• You have experience in the cultivation and handling of mammalian cells and the development of production cell lines 
• You have a very good understanding and laboratory experience of various molecular biological methods

Preferred qualifications

• Experience in supervision
• Experience of teaching
• It is advantageous if you have awareness of diversity and equal treatment issues with a particular focus on gender equality 

Great emphasis will be placed on personal skills.

Trade union representatives

Contact information to trade union representatives.

To apply for the position

Log into KTH's recruitment system in order to apply for this position. You are responsible to ensure that your application is complete according to the instructions in the ad. Your complete application must be received at KTH no later than the last day of application.

Your complete application must be received by KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time). 

About the employment

The employment is valid for a limited time according to the agreement - for up to 12 months, with access according to agreement.

Other information

Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.

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According to The Protective Security Act (2018-585), the candidate must undergo and pass security vetting if the position is placed in a security class. Information regarding whether the position is subject to such a classification will be provided during the recruitment process.

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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence